Dental and oral implications of prescribed Oral Nutritional Supplements for disease related malnutrition- A systematic review

BACKGROUND AND OBJECTIVES: The use of Oral Nutritional Supplements (ONS) is widespread among patients with long- and short-term medical conditions. Although ONS serve an important purpose in the management malnutrition, their effect on oral hard soft tissues not well understood. aim this article to conduct analysis available literature relating impact environment. METHODS: This study was conducted following Preferred Reporting Items for Systematic Review Meta-Analysis (PRISMA) guidelines adapted by Liberati. PICO question as follows: Population: Individuals (both children adults) Intervention: Use Comparison: taking Outcome: Increased risk disease (specifically dental caries, periodontal or candida) research “Are people who take at higher diseases than general population?” Eligibility criteria results obtained from search were filtered, according these inclusion exclusion criteria: Inclusion • prescribed All studies included, including, case– control, cohort, cross-sectional case studies. Studies included if they directly compared association between health i.e. Effect environment had be one aims human subjects vitro experiments Published English language 1960 present day Exclusion articles series excluded including other nutritional supplements such vitamin herbal included. Other supplemental feeding methods enteral parenteral examined 4 databases searched: Medline (via Ebsco), Embase, Web Science Core Collection, Google Scholar. Risk bias assessed using ROBINS-I tool. RESULTS: A total 58 records identified through searching bibliographies. 50 publications review, based title abstract. full text eight eligibility. No answered primary systematic review. Three discussed secondary review qualitative main outcome first showed that cariogenic potential milk due it’s acidogenicity. However, there no statistical difference dentine demineralisation significant viable micro-organisms present. second Escherichia coli, Staphylococcus aureus C. albicans all grew room temperature dairy-based collected, also juice which protein-free lipid-free. third “potentially cariogenic” enamel. DISCUSSION: Two deemed being “low” bias, however another “serious” level bias. stressed possibility caused supplements, enough imply causation. Due high sugar content known implications this, it would beneficial carry out more into area.